Molecular Diagnosis of Wound Infections

Problem

  • Chronic, non-healing wounds such as diabetic foot ulcers and venous stasis ulcers are often infected with a polymicrobial biofilm
  • Traditional microbiology culture fails to identify components of the biofilm
    • Anerobic bacteria and gram negative bacteria are underrepresented in complicated wounds using traditional culture methods
    • Low abundance organisms are difficult to grow from a complex mixture but may be an important component of the wound bed
  • Cultures are highly affected by pre-analytic handling and need to be in the lab within 2 hours of collection for accurate results

Solution

  • Compass Laboratory Services (Accredited by the College of American Pathologists) offers state of the art molecular diagnostic methods for identification of clinically relevant pathogens
    • Use of quantitative PCR increases the diagnostic accuracy of testing

• Increased sensitivity and specificity

  • Faster turn around time as compared to traditional microbiology culture. Results available within 24 hours of sample receipt
  • Easy to understand report with specific treatment guidelines
  • Multiple panels designed to offer providers affordable, state of the art diagnostics

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Molecular Diagnosis of Wound Infections

Problem Chronic, non-healing wounds such as diabetic foot ulcers and venous stasis ulcers are often infected with a polymicrobial biofilm Traditional microbiology culture fails to